The mishap occurred shortly after 6 p.m. near the Fairfield-Bridgeport line.
The injured were taken to Bridgeport Hospital and St. Vincent's Medical Center.
Connecticut Governor Dannel P. Malloy tweeted: "60 people have been taken to the hospital. There are five people in critical condition, one in very critical condition."
Crews from Metro North will start repairing the track on Saturday.
"On Saturday, investigators from the National Transportation Safety Board will start working to piece together how the crash occurred while crews from Metro North start to repair the tracks," Connecticut Post reported.
--IBNS (Posted on 18-05-2013)