health-news

New urine test to detect blood clots developed

Washington, Oct 17 : A team of engineers with an Indian origin researcher have developed a way to detect blood clots, which can form in anyone who sits on a plane for a long time and which often remain undetected until they break free and cause a stroke or heart attack, by using a simple urine test.


The noninvasive diagnostic, relies on nanoparticles that detect the presence of thrombin, a key blood-clotting factor.

Senior author of the paper, Sangeeta Bhatia from Massachusetts Institute of Technology and the John and Dorothy Wilson Professor of Biochemistry, said that such a system could be used to monitor patients who are at high risk for blood clots.

Bhatia and her colleagues developed their new test based on a technology they first reported last year for early detection of colorectal cancer.

The system consists of iron oxide nanoparticles, which the Food and Drug Administration has approved for human use, coated with peptides (short proteins) that are specialized to interact with thrombin.

After being injected into mice, the nanoparticles travel throughout the body. When the particles encounter thrombin, the thrombin cleaves the peptides at a specific location, releasing fragments that are then excreted in the animals' urine.

Once the urine is collected, the protein fragments can be identified by treating the sample with antibodies specific to peptide tags included in the fragments. The researchers showed that the amount of these tags found in the urine is directly proportional to the level of blood clotting in the mice's lungs.

The study is published in the journal ACS Nano.

--ANI (Posted on 18-10-2013)

health-news headlines

Malnutrition not priority for most parties: CRY

Testosterone levels in womb may impact your health

Bone marrow can cure blood disorders

Heart's development doesn't stop with birth

Mothers! Take a break from fish for healthier babies

Pancreatic, biliary cancers difficult to treat: Experts

NHC showcase bone marrow transplant to cure blood disorders

Probiotic use for infant colic 'not effective in reducing symptoms'

Laugh your way to improved short-term memory

'Chaperone' compounds could help treat Alzheimer's

Source of most cases of invasive bladder cancer identified

Daytime napping may lead to early death: Study

Quick Links: Goa | Munnar | Pondicherry | Free Yearly Horoscope '2014

Comments

Your e-mail:


Your Full Name:


Type verification image:
verification image, type it in the box

Message:

Back to Top