"Traditionally, migraine has been considered a benign disorder without long-term consequences for the brain," study author Messoud Ashina, MD, PhD, with the University of Copenhagen in Denmark, said.
"Our review and meta-analysis study suggests that the disorder may permanently alter brain structure in multiple ways," the researchers said.
The study found that migraine raised the risk of brain lesions, white matter abnormalities and altered brain volume compared to people without the disorder.
The association was even stronger in those with migraine with aura.
For the meta-analysis, researchers reviewed six population-based studies and 13 clinic-based studies to see whether people who experienced migraine or migraine with aura had an increased risk of brain lesions, silent abnormalities or brain volume changes on MRI brain scans compared to those without the conditions.
The results showed that migraine with aura increased the risk of white matter brain lesions by 68 percent and migraine with no aura increased the risk by 34 percent, compared to those without migraine.
The risk for infarct-like abnormalities increased by 44 percent for those with migraine with aura compared to those without aura.
Brain volume changes were more common in people with migraine and migraine with aura than those with no migraines.
The study is published in Neurology, the medical journal of the American Academy of Neurology.
--ANI (Posted on 29-08-2013)