According to sources, the two Hollywood starlets who were once very close friends have been missing a series of key events in each other's lives, News.com.au reported.
Sources revealed that the friendship deteriorated after Cox separated from her husband David Arquette, who is a close friend of Aniston, in 2010.
The 'Scream' series actress has been absent from the 'Horrible Bosses' actress's Chateau Marmont 43rd birthday party, her engagement party to Justin Theroux and, most recently, the bash Aniston threw for her fiance's birthday, which have fuelled the rumors of their estranged relation.
Aniston, who played Rachel Greene in the Friends series is godmother to Cox's daughter Coco. But recently the distance between the two has increased manifold.
Cox, who played Monica Geller in the hit series, had reportedly helped Aniston get through her divorce from Brad Pitt in 2005 and together spent several holidays in Mexico.
--ANI (Posted on 15-08-2013)