health-news

White blood cells' role in cancer revealed

Washington, July 02 : A new study has found that cancer cells can get activated and spread by infection-fighting white blood cells.


"We are the first to identify this entirely new way that cancer spreads," senior author Dr. Lorenzo Ferri, MUHC director of the Division of Thoracic Surgery and the Upper Gastrointestinal (GI) Cancer Program said.

"What's equally exciting is medications already exist that are being used for other non-cancer diseases, which may prevent this mechanism of cancer spread or metastasis," he explained.

According to Dr. Ferri, the next steps are to validate if these medicines will work for the prevention and treatment of cancer metastasis, and then to determine the optimal timing and dosing.

Dr. Ferri and his colleagues from McGill University and the University of Calgary used both cultured cells and mouse models of cancer to show that there is a relationship between infection, a white blood cell response (inflammation) and metastasis.

A web-like network called Neutrophils Extracellular Traps (NETs), is produced by white blood cells (neutrophils) in response to an infection and this normally traps and kills invading pathogens, such as bacteria.

The researchers went one step further and showed that breaking down the neutrophil web is achievable by using certain medication.

Furthermore, in mice with cancer, markedly less tumour growth and metastasis occurred after the medication was administered.

This finding was true for a number of different cancer types, suggesting that neutrophil webs may be a common pathway involved in the spreading of many cancers.

"Our study reflects a major change in how we think about cancer progression and, more importantly, how we can treat it," Dr. Ferri said.

--ANI (Posted on 02-07-2013)

health-news headlines

Four must eat white vegetables

Obesity can aggravate bone and muscle loss

'Severely infectious' bacterial strain can survive in contact lens solution

People undergoing weight loss surgery experience changes in appetite, taste and smell

Masculine boys and feminine girls likelier to engage in behaviors that poses cancer risk

Embrace daily massage to improve health

Internet use to ward off depression among elderly

BMI linked to postmenopausal breast cancer regardless of body shape

Protein crucial for sperm-egg fertilization discovered

Now, drug that combats measles and prevents virus from spreading

How memories stick together

Leeches can fix torn ear!

Quick Links: Goa | Munnar | Pondicherry | Free Yearly Horoscope '2014

Comments

Your e-mail:


Your Full Name:


Type verification image:
verification image, type it in the box

Message:

Back to Top