technology-news

Vital protein to stop tumour growth identified

London, Jan 4 : In what can be called a major relief for scientists working on cancer research, a new study has reassured the potential of a protein that can be targetted to stop tumour growth.


Scientists from the University of East Anglia in Britain have found that researchers should not give up on the beta3-integrin protein, which has been a major target in cancer drug design for the last two decades.

"These findings have re-established the expression of beta3-integrin as a valid clinical target when treating cancer. Efforts must now be re-focused to either develop new drugs to target beta3-integrin, or figure out how to more effectively use the drugs that already exist," said Stephen Robinson of the School of Biological Sciences, University of East Anglia.

The research, published in American Heart Association's journal "Circulation Research", also explained why the most advanced version of avß3-integrin - a stem cell marker and driver of tumour cell resistance - failed clinical trials to treat aggressive forms of brain cancer.

"This research helps to explain why these very promising drugs aren't meeting with the success that was anticipated and it suggests a way forward - how to make them work better," Robinson said.

"We have shown how tumours continue to grow despite treatment which should block blood vessel recruitment. They modulate how they are recruiting their blood vessels by using a different pathway from the one that is being targeted," he said.

"Our research also shows that timing is critical when targeting the protein beta3-integrin," he added.

--IANS (Posted on 04-01-2014)

technology-news headlines

LED bulbs can make your white shirt ineffective!

Revealed: What distracts your brain while driving

'Asteroid impact stored proof of life in glasses on earth'

Ancient tundra landscape discovered under Greenland Ice Sheet

NASA's Kepler Space Telescope finds Earth's twin

Concrete that never gets a crack!

Tiny robots to help you perform daily chores

Fossil of 325-million-year-old shark-like specie sheds light on evolution of jaws

Soon, wireless power zones to charge your phone

Soon, cheap computers and 'throwaway' cell phones

Scientists identify target for treating dengue

Waste sulphur to produce cheap infra-red devices

Quick Links: Goa | Munnar | Pondicherry | Free Yearly Horoscope '2014

Comments

Your e-mail:


Your Full Name:


Type verification image:
verification image, type it in the box

Message:

Back to Top