health-news

Study reveals new strategy for treating pancreatic cancer

London, Dec 25 : Scientists have found a new strategy to selectively kill pancreatic cancer cells without harming normal cells, a study says.


Scientists from The University of Manchester and part of the Manchester Cancer Research Centre believe they have discovered a new way to make chemotherapy treatment more effective for pancreatic cancer patients.

Pancreatic cancer is an aggressive cancer with poor prognosis and limited treatment options and is highly resistant to chemotherapy and radiotherapy.

But researchers believe they have found an effective strategy for selectively killing pancreatic cancer while sparing healthy cells which could make treatment more effective.

Jason Bruce, from the Physiological Systems and Disease Research Group, who led the research, said: "Pancreatic cancer is one of the most aggressive and deadly cancers. Most patients develop symptoms after the tumour has spread to other organs.

To make things worse, pancreatic cancer is highly resistant to chemotherapy and radiotherapy. Clearly a radical new approach to treatment is urgently required. We wanted to understand how the switch in energy supply in cancer cells might help them survive."

The research, published in The Journal of Biological Chemistry this month, found pancreatic cancer cells may have their own specialised energy supply that maintains calcium levels and keeps cancer cells alive.

Maintaining a low concentration of calcium within cells is vital to their survival and this is achieved by calcium pumps on the plasma membrane, reports Science Daily.

This calcium pump, known as PMCA, is fuelled using ATP -- the key energy currency for many cellular processes.

"Designing drugs to cut off this supply to the calcium pumps might be an effective strategy for selectively killing cancer cells while sparing normal cells within the pancreas."

--IANS (Posted on 25-12-2013)

health-news headlines

Anti-depressants during pregnancy linked to autism and developmental delays in boys

Girls' mental health suffers when romances play out differently than they imagined

Now, faster, cheaper blood test to accurately diagnose asthma

Genetic therapy may repair spinal chord: Study

Viagra ice cream for instant erection?

Antibiotics beneficial for undernourished kids: Study

Go for food with rough texture for a healthy you!

Rice eaters have better diets

Lack of awareness about heamophilia still persists (April 17 is World Haemophilia Day)

Learn from hunters how lifestyle affects gut bacteria

Simple blood test can diagnose asthma: Study

Simple blood test can diagnose asthma: Study

Quick Links: Goa | Munnar | Pondicherry | Free Yearly Horoscope '2014

Comments

Your e-mail:


Your Full Name:


Type verification image:
verification image, type it in the box

Message:

Back to Top