New study provides answers to fundamental questions about Alzheimer's

Washington, December 23 : A new study has revealed fundamental issues about Alzheimer's disease, including where it starts, why it starts there, and how it spreads.

Researchers from Columbia University Medical Center have found that it begins specifically in the lateral entorhinal cortex, which is considered to be a gateway to the hippocampus, which plays a key role in the consolidation of long-term memory, among other functions.

The study has revealed that the LEC is especially vulnerable to Alzheimer's because it normally accumulates tau, which sensitizes the LEC to the accumulation of APP, and together, they damage neurons in the LEC, setting the stage for Alzheimer's.

The findings have also shown that the disease spreads from the LEC directly to other areas of the cerebral cortex, in particular, the parietal cortex, over time.

It could also improve early detection of the disease and gauge the effectiveness of the drugs.

The study was published today in the online edition of the journal Nature Neuroscience.

--ANI (Posted on 23-12-2013)

health-news headlines

Cellulite facts worth knowing

Want to de-stress? Sex can help you

People are more concerned about their health at start of the week than weekends

Brain's anti-distraction system found

Chronic inflammation associated with aggressive prostate cancer

Easter chocolate can be good for health

'Smart' device that engineers cells to kill cancer

Lost stem cells are replaced by non-stem cells: Study

Brown fat breakthrough may be 'holy grail' of weight loss

Tuberculosis drug could also help treat other diseases

New method to fight Malaria drug resistance discovered

Dengue fever could soon be history

Quick Links: Goa | Munnar | Pondicherry | Free Yearly Horoscope '2014


Your e-mail:

Your Full Name:

Type verification image:
verification image, type it in the box


Back to Top