Why obese people are unable to lose weight?
Melbourne, Feb. 6 : Scientists have pinpointed exactly why obese people don't lose much weight despite going on a vigorous diet.
Researchers have found that a chemical known as the Neuropeptide (NPY) - which stimulates appetite - plays a major role in controlling whether the body burns or conserves energy.
The study by researchers at Sydney's Garvan Institute of Medical Research, shows that when the body takes in less energy or is on a diet, high levels of Neuropeptide signal the body that it is in a starvation mode, and the body starts storing as much energy as possible, News.com.au reported.
Co-author of the study, Professor Herzog, said that with obesity being a major epidemic in the community, researchers have found it challenging to find ways of tricking the body into losing weight because of NPY.
He said that now that they had identified the exact brain circuitry, drugs can be developed to target and control these types of neurons.
Herzog said that it was important to note that the study also showed that fad diets simply did not work and that weight loss needed to be done over a long period of time and that's what people underestimated.
The study has been published in the journal Cell Metabolism.