Fat and prone to illness? Don't worry, just vibrate
You can reap the benefits of exercise such as improved immunity without exerting yourself thanks to low intensity vibrations - as shown in studies on mice.
"Mechanical signals can help restore an immune system compromised by obesity," said Clinton Rubin, study author and biomedical engineer from Stony Brook University, New York.
"While it is well known that obesity can cripple many physiologic systems, this work suggests that mechanical signals -- in the absence of drugs -- can help combat this disease," added Rubin, the FASEB Journal reports.
That these mechanical signals are so brief, and so mild, is further evidence of how exquisitely tuned our body is to external signals, and that remaining active -- climbing stairs at work, taking a walk at lunch, standing while reading a book -- will help achieve and retain good health, the researcher said.
Rubin and colleagues fed a group of adult mice a high fat diet for seven months to make them obese. At the end of this first phase of the experiment, the damage to the immune and skeletal systems of the obese mice was significant, decreasing B- and T-immune cellpopulations in the blood, and markedly accelerating the loss of bone, according to a Stony Brook statement.
The second phase began after the mice were obese relative to regular controls, with the creation of a sub-group that was subjected to daily 15-minute bouts of low-intensity vibration, barely perceptible to the human touch.
Results showed that the vibration intervention helped to rescue both the immune and skeletal systems, returning them toward outcomes measured in mice that were fed a regular diet.
This study provides evidence that obesity markedly reduces the production of B- and T-cells and that brief daily exposure to low magnitude mechanical signals rescues B- and T-cell populations, even in a mouse that is already obese.