Men with excess belly fat at risk for bone loss
Washington, November 29(ANI)
Excess belly fat is not only a risk factor for heart disease and diabetes, it is also a risk factor for bone loss and decreased bone strength in men, a new study has revealed.
According to the National Center for Health Statistics, more than 37 million American men over age 20 are obese. Obesity is associated with many health problems, including cardiovascular diseases, diabetes, high cholesterol, asthma, sleep apnea and joint diseases. Yet despite all the health issues, it was commonly accepted that men with increased body weight were at lower risk for bone loss.
"Most studies on osteoporosis have focused on women. Men were thought to be relatively protected against bone loss, especially obese men," said Miriam Bredella, M.D., radiologist at Massachusetts General Hospital and associate professor of radiology at Harvard Medical School in Boston.
But not all body fat is the same. Subcutaneous fat lies just below the skin, and visceral or intra-abdominal fat is located deep under the muscle tissue in the abdominal cavity. Genetics, diet and exercise are all contributors to the level of visceral fat that is stored in the body. Excess visceral fat is considered particularly dangerous, because in previous studies it has been associated with increased risk for heart disease.
After the Osteoporotic Fractures in Men Study -- a multi-center observational study designed to determine risk factors for osteoporosis -- indicated that male obesity was associated with fracture risk, the researchers wanted to quantify belly fat and study its impact on bone strength.
Dr. Bredella and her team evaluated 35 obese men with a mean age of 34 and a mean body mass index (BMI) of 36.5. The men underwent CT of the abdomen and thigh to assess fat and muscle mass, as well as very high resolution CT of the forearm and a technique called finite element analysis (FEA), in order to assess bone strength and predict fracture risk.
In the study, the FEA analysis showed that men with higher visceral and total abdominal fat had lower failure load and stiffness, two measures of bone strength, compared to those with less visceral and abdominal fat. There was no association found between age or total BMI and bone mechanical properties.
"We were not surprised by our results that abdominal and visceral fat are detrimental to bone strength in obese men. We were, however, surprised that obese men with a lot of visceral fat had significantly decreased bone strength compared to obese men with low visceral fat but similar BMI," Dr. Bredella said.
The results also showed that muscle mass was positively associated with bone strength.
The study was presented at the annual meeting of the Radiological Society of North America (RSNA).