Viral infections may soon be history
Scientists have identified a mechanism how some viruses protect themselves from the immune system's efforts to stop infections.
This new finding could pave new ways to treating viral infections.
Viruses have well-known strategies for slipping past the immune system. These include faking or stealing a molecular identification badge that prevents a cell from recognizing a virus.
Scientists at Washington University School of Medicine in St. Louis and elsewhere have found some viruses have another trick. They can block the immune system protein that checks for the identification badge.
The blocking structure is called a stem-loop, found at the beginning of the virus's genetic material.
This is the first time scientists have found an immune-fighting mechanism built directly into the genetic material of a virus.
They are looking for ways to disable it and searching for similar mechanisms that may be built into the genetic material of other disease-causing microorganisms.
"When the stem-loop is in place and stable, it blocks a host cell immune protein that otherwise would bind to the virus and stop the infectious process," senior author Michael Diamond, MD, PhD, professor of medicine, said.
"We found that changing a single letter of the virus's genetic code can disable the stem-loop's protective effects and allow the virus to be recognized by the host immune protein. We hope to find ways to weaken the stem-loop structure with drugs or other treatments, restoring the natural virus-fighting capabilities of the cell and stopping or slowing some viral infections," he added.
(Posted on 03-02-2014)
Information on States of India:
Andaman Nicobar | Andhra Pradesh | Assam | Bihar | Chandigarh | Chhattisgarh | Dadar Nagar Haveli | Daman Diu | Delhi | Goa | Gujarat | Haryana | Himachal Pradesh | Jammu Kashmir | Jharkhand | Karnataka | Kerala | Lakshadweep | Madhya Pradesh | Maharashtra | Manipur | Meghalaya | Mizoram | Nagaland | Orissa | Pondicherry | Punjab | Rajasthan | Sikkim | Tamil Nadu | Tripura | Uttar Pradesh | Uttaranchal | West Bengal
INDIA REGIONAL MAPS:
Andhra Pradesh Travel Map | Bihar Travel Map | Goa Travel Map | Gujarat Travel Map | Haryana Travel Map | Himachal Pradesh Map | Karnataka Travel Map | Kerala Travel Map | Maharashtra Travel Map | Punjab Travel Map | Rajasthan Travel Map | Sikkim Travel Map | Tamil Nadu Travel Map | Uttar Pradesh Travel Map | West Bengal Travel Map |
MORE MAPS OF INDIA:
INDIA CITY MAPS:
KERALA TRAVEL MAPS: