Washington, Feb 2 ANI | 8 months ago

A chemical that is found in fruits and vegetables from strawberries to cucumbers apparently stops memory loss that accompanies Alzheimer's disease in mice, a new study has claimed.


Scientists at the Salk Institute for Biological Studies have discovered in experiments on mice which normally develop Alzheimer's symptoms less than a year after birth, that a daily dose of the compound----a flavonol called fisetin----prevented the progressive memory and learning impairments.

The drug, however, did not alter the formation of amyloid plaques in the brain, accumulations of proteins which are commonly blamed for Alzheimer's disease.

The new finding suggests a way to treat Alzheimer's symptoms independently of targeting amyloid plaques.

"We had already shown that in normal animals, fisetin can improve memory," Pamela Maher, a senior staff scientist in Salk's Cellular Neurobiology Laboratory who led the new study, said.

"What we showed here is that it also can have an effect on animals prone to Alzheimer's," she said.

More than a decade ago, Maher discovered that fisetin helps protect neurons in the brain from the effects of aging. She and her colleagues have since----in both isolated cell cultures and mouse studies----probed how the compound has both antioxidant and anti-inflammatory effects on cells in the brain. Most recently, they found that fisetin turns on a cellular pathway known to be involved in memory.

"What we realized is that fisetin has a number of properties that we thought might be beneficial when it comes to Alzheimer's," Maher said.

The research is published in the journal Aging Cell.

(Posted on 03-02-2014)

Share This Page:


Post your comments


Information on States of India:

Andaman Nicobar | Andhra Pradesh | Assam | Bihar | Chandigarh | Chhattisgarh | Dadar Nagar Haveli | Daman Diu | Delhi | Goa | Gujarat | Haryana | Himachal Pradesh | Jammu Kashmir | Jharkhand | Karnataka | Kerala | Lakshadweep | Madhya Pradesh | Maharashtra | Manipur | Meghalaya | Mizoram | Nagaland | Orissa | Pondicherry | Punjab | Rajasthan | Sikkim | Tamil Nadu | Tripura | Uttar Pradesh | Uttaranchal | West Bengal

INDIA REGIONAL MAPS:

Andhra Pradesh Travel Map | Bihar Travel Map | Goa Travel Map | Gujarat Travel Map | Haryana Travel Map | Himachal Pradesh Map | Karnataka Travel Map | Kerala Travel Map | Maharashtra Travel Map | Punjab Travel Map | Rajasthan Travel Map | Sikkim Travel Map | Tamil Nadu Travel Map | Uttar Pradesh Travel Map | West Bengal Travel Map |

MORE MAPS OF INDIA:

Airports of India | Districts of India | India Pilgrim Centers | Tourism Map of India | National Highways in India | India Railway Routes |

INDIA CITY MAPS:

Ahmadabad | Bangalore | Chennai | Coimbatore | Delhi | Hyderabad/Secunderabad | Kochi | Kolkata | Mumbai | Pondicherry | Pune | Surat |

KERALA TRAVEL MAPS:

Alappuzha | Ernakulam | Idukki | Kannur | Kasaragod | Kollam | Kottayam | Kozhikode | Malappuram | Palakkad | Pathanamthitta | Thiruvananthapuram | Thrissur | Wayanad |