Simple ultrasound may help predict heart attack risk
Washington, Aug 20 : Repeat exams using simple and inexpensive ultrasound can help
identify patients at high risk for a heart attack or other adverse cardiovascular events,
according to a group of researchers.
The team led by Markus Reiter at Medical University Vienna in Austria performed
ultrasound imaging on the carotid arteries of 1,268 patients who were asymptomatic but at
high risk for cardiovascular disease.
By determining the amount of plaque built up in the two vessels that supply blood to
the head and neck, 574 patients were found to have carotid artery disease.
"Determining the degree of stenosis, or how much the artery has narrowed, is
insufficient to predict patient risk," said lead researcher Markus Reiter, M.D., from the
Department of Angiography and Interventional Radiology at Medical University Vienna in
Austria.
"We know that the majority of cardiovascular and cerebrovascular events occur in
patients whose blood vessels are less than 70 percent narrowed," he added.
With the help of ultrasound images and computer-assisted gray scale median (GSM)
measurements, the research team examined the density of the plaque lining the carotid
arteries.
Plaques that appear dark on ultrasound images and have a low GSM level are suggested to
be associated with an increased risk for clinical complications and seem to represent
unstable plaques, which are more likely to rupture or burst.
The study's follow-up ultrasounds revealed that GSM levels had decreased in 230 (40
percent) of the patients. Of those, 85 experienced a major adverse cardiovascular event
within three years of the second ultrasound.
In 344 of the patients, ultrasound GSM levels had increased between the baseline and
follow-up ultrasound examinations. Of those patients, 92 experienced a major adverse
cardiovascular event.
"Patients with a reduction in GSM levels from their baseline ultrasound to the
follow-up ultrasound exhibited a significantly increased risk for near-future adverse
event compared to patients with increasing GSM levels," said Reiter.
"This technique will give us additional information to use in selecting patients that
need aggressive treatment," he added.
The study is published in the September issue of the journal Radiology.
--ANI
