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Health News Updated Oct 1, 2025

Young night shift workers more at risk of developing kidney stones: Study

A groundbreaking study has unveiled the increased kidney stone risk for night shift workers, particularly among younger employees. Researchers discovered a 15% higher likelihood of developing kidney stones linked to irregular work schedules and lifestyle factors. The study, published in Mayo Clinic Proceedings, examined over 220,000 participants to understand the complex relationship between shift work and health outcomes. Experts emphasize the critical role of circadian rhythm disruption in potential medical complications.

New Delhi, Oct 1

Young night shift workers are more at risk of developing kidney stones, according to a study.

The findings, published in the journal Mayo Clinic Proceedings, showed that the shift workers have a 15 per cent higher risk of developing kidney stones, especially younger workers and those with low levels of manual labour.

Body mass index (BMI), fluid intake, and other lifestyle factors play key roles in the occurrence of kidney stones.

Long-term shift work, characterised by an irregular work schedule outside conventional daytime work hours, particularly night shift work, can disrupt workers' circadian rhythms, impact metabolism and hormone secretion, alter lifestyles, and lead to adverse health outcomes.

"We found that shift work is associated with a higher risk of kidney stone events; an association that is partially mediated by several lifestyle factors, including smoking, sleep, fluid intake, and BMI," said lead investigator Yin Yang, Department of Epidemiology, Sun Yat-sen University in China.

Using data from over 220,000 participants, the researchers in the current study analysed the association between shift work, including its type, frequency, and duration, and kidney stone events over a median follow-up period of 13.7 years.

Kidney stone disease is a common and preventable urological disease, with an estimated prevalence ranging from 1 per cent to 13 per cent in different regions across the world. It has been associated with an elevated risk of cardiovascular diseases, chronic kidney disease, and renal failure, all of which impose a substantial long-term disease burden.

Kidney stone formation is influenced by several intrinsic and extrinsic factors, including genetics, dietary characteristics, physical activity, BMI, and other lifestyle behaviours.

In an accompanying editorial, Felix Knauf, from the Division of Nephrology and Hypertension, Mayo Clinic, US, pointed out that the highest risk for kidney stones occurred in individuals involved with night shift work.

"A central effect of shift work is the disruption of circadian rhythms. Homeostasis and health are underpinned by physiologic systems, virtually all of which are governed by the biologic clock that dictates the periodicity, tempo, and physiologic effects of circadian rhythms," Knauf said.

— IANS

Reader Comments

Rohit P

This is so true! My cousin who works night shifts in a call center developed kidney stones last year. The doctors specifically mentioned his irregular schedule and poor water intake as contributing factors. Stay hydrated, friends! 💧

Arjun K

While the study is important, I wish it had more specific recommendations for Indian workers. Our dietary patterns are different - we consume more spicy food and tea/coffee during night shifts. More localized research would be helpful.

Sarah B

Working in IT night shifts in Bangalore, I've seen many colleagues with health issues. Companies need to implement better wellness programs and regular health check-ups for night shift workers. Health should be prioritized over profits.

Vikram M

The 15% higher risk is quite significant when you consider how many young Indians work night shifts in IT, BPO, healthcare and manufacturing. This should be a wake-up call for both employers and employees. 🚨

Kavya N

My doctor always emphasizes drinking 3-4 liters of water daily, especially for night shift workers. This study reinforces that advice. Simple lifestyle changes can make a big difference in preventing kidney stones. 👍

We welcome thoughtful discussions from our readers. Please keep comments respectful and on-topic.

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