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Health News Updated Apr 22, 2025

AI algorithm can help identify high-risk heart patients: Study

A groundbreaking AI algorithm developed by Mount Sinai researchers can now accurately predict heart disease risk with unprecedented precision. The technology, called Viz HCM, assigns numeric probabilities to help identify patients with hypertrophic cardiomyopathy (HCM) before critical symptoms develop. By providing more meaningful risk assessments, the algorithm could revolutionize early cardiac intervention and potentially prevent serious complications like sudden cardiac death. This innovation represents a significant advancement in using artificial intelligence to improve personalized medical diagnostics and patient care.

New York, April 22

, on Tuesday said they have calibrated an artificial intelligence (AI) algorithm to quickly and more specifically identify patients with the condition and flag them as high risk for greater attention during doctor’s appointments.

The algorithm, known as Viz HCM, had previously been approved by the Food and Drug Administration (FDA) for the detection of HCM on an electrocardiogram (ECG).

The Mount Sinai study, published in the journal NEJM AI, assigns numeric probabilities to the algorithm’s findings.

For example, while the algorithm might previously have said "flagged as suspected HCM" or "high risk of HCM," the Mount Sinai study allows for interpretations such as, "You have about a 60 percent chance of having HCM," said Joshua Lampert, Director of Machine Learning at Mount Sinai Fuster Heart Hospital.

As a result, patients who had not previously been diagnosed with HCM may be able to get a better understanding of their individual disease risk, leading to a faster and more individualized evaluation, along with treatment to potentially prevent complications such as sudden cardiac death, especially in young patients.

“This is an important step forward in translating novel deep-learning algorithms into clinical practice by providing clinicians and patients with more meaningful information. Clinicians can improve their clinical workflows by ensuring the highest-risk patients are identified at the top of their clinical work list using a sorting tool,” said Lampert, Assistant Professor of Medicine (Cardiology, and Data-Driven and Digital Medicine) at the Icahn School of Medicine at Mount Sinai.

HCM impacts one in 200 people worldwide and is a leading reason for heart transplantation. However, many patients don’t know they have the condition until they have symptoms and the disease may already be advanced.

“This study reflects pragmatic implementation science at its best, demonstrating how we can responsibly and thoughtfully integrate advanced AI tools into real-world clinical workflows,” said co-senior author Girish N Nadkarni, Chair of the Windreich Department of Artificial Intelligence and Human Health and Director of the Hasso Plattner Institute for Digital Health.

— IANS

Reader Comments

Sarah K.

This is amazing progress! My cousin was diagnosed with HCM too late and had to get a transplant. If this AI can catch it earlier, it could save so many lives. 🙏

Mike T.

Interesting study but I wonder about false positives. Wouldn't telling someone they have a 60% chance cause unnecessary stress? The tech sounds promising but needs careful implementation.

Jamal R.

As someone in healthcare tech, this is exactly how AI should be used - augmenting human judgment with data, not replacing doctors. The probability scoring is a game changer!

Lisa P.

Hope this becomes standard soon! My ECG last year was "normal" but I still had symptoms. Turns out I have mild HCM. Maybe this AI would've caught it earlier 🤔

David W.

The 1 in 200 stat surprised me. Makes you wonder how many people are walking around undiagnosed. Great to see tech being used for preventative care like this.

We welcome thoughtful discussions from our readers. Please keep comments respectful and on-topic.

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