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Russia Pioneers Cell-Based Eardrum Repair in World-First Clinical Use

Sechenov University in Moscow has initiated the world's first clinical application of a cell-based product to repair perforated eardrums. The technology uses a patient's own cells to create tissue equivalents that regenerate the membrane. The 40-minute procedure shows promising early results with favourable recovery and no complications reported. Researchers state this platform technology could be adapted to regenerate other tissues, marking a major shift from experimental research to practical medicine.

Key Points: World-First Cell Therapy for Eardrum Repair Begins in Russia

  • World-first clinical use of cell product for eardrum
  • Uses patient's own adipose tissue cells
  • 40-minute procedure faster than standard surgery
  • Platform tech could regenerate other organs
  • Addresses common perforations from infection or trauma
2 min read

Russia begins clinical use of cell-based technology for eardrum repair

Sechenov University begins clinical use of a patient's own cells to regenerate damaged eardrums, a breakthrough in regenerative medicine.

"the institution is the only medical university in Russia to have completed the entire translational pathway - Petr Glybochko"

Moscow, January 11

The Clinical Centre of IM Sechenov First Moscow State Medical University, commonly known as Sechenov University, has begun performing innovative eardrum repair procedures using tissue equivalents created from patients' own cells.

According to the university's official portal, this is the world's first reported clinical application of a cell-based medicinal product (CBMP) for the regeneration of the tympanic membrane.

The breakthrough marks a significant milestone in regenerative medicine.

Sechenov University Rector Petr Glybochko said the institution is the only medical university in Russia to have completed the entire translational pathway, from fundamental research to certified production of a cell product and its clinical use within its own medical facility, as reported by TV BRICS.

The research is being conducted under state programmes supporting science and education.

The technology involves extracting cells from a patient's adipose tissue and forming them into cell spheroids. These spheroids are implanted along with a resorbable membrane at the site of the damaged eardrum. Over time, the membrane dissolves and is replaced by the patient's own regenerated tissue, which closely matches the structure and function of a natural eardrum.

Clinical data show that the procedure takes approximately 40 minutes, making it significantly faster than conventional tympanoplasty.

Early results have been encouraging, with the first patients experiencing favourable post-operative recovery and no reported complications.

Medical experts note that tympanic membrane perforation affects four to five people per 1,000, often resulting from infections, physical trauma, or sudden changes in pressure.

Existing surgical techniques are complex and do not always produce stable outcomes, with graft failure rates ranging between 10 and 20 per cent.

Researchers at Sechenov University said the new development covers the entire innovation cycle, from cell isolation to clinical application, enabling a shift from experimental research to practical medicine.

They added that the platform technology could later be adapted for the regeneration of other organs and tissues, significantly expanding the future potential of cell-based therapies.

- ANI

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Reader Comments

R
Rohit P
Wow, 40 minutes vs traditional surgery! Russia is making big strides. I wonder when AIIMS or other Indian medical institutes will start similar research. We have brilliant doctors here too.
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Aman W
Good development, but the real test is long-term success and cost. Will it be affordable for the common man? In India, many still struggle with basic healthcare access. Hope the focus is on making such treatments economical.
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Sarah B
Fascinating read. The potential to adapt this for other organs is the most exciting part. Science truly has no borders. Kudos to the researchers.
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Vikram M
Using adipose tissue... amazing! My father had a tympanoplasty years ago, recovery was long. This sounds much better. Hope Indian medical tourists can benefit from this in Moscow soon.
K
Karthik V
A welcome step forward. However, the article mentions state programmes in Russia. India also needs strong, consistent government funding for such translational research to move from labs to hospitals. Our CSIR and DBT institutes are capable.

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