According to Georgia Hodes, PhD, abstract, a molecule in the immune system may contribute to depression, suggesting a potential biomarker for the disease.
Yann Mineur, PhD, abstract revealed that decreasing a chemical signal in the amygdala, a brain area associated with emotional processing, produces antidepressant-like effects in mice.
Karen Scott, PhD, abstract suggested that MicroRNAs, tiny molecules that alter gene expression, correlate with how mice respond to socially stressful situations that cause depressive-like behaviour. The findings may help determine why some people are more likely to suffer from depression than others.
Other recent findings discussed show that a pathway between two brain regions, the amygdala and the hippocampus, plays a significant role in anxiety. Shutting down this connection can decrease anxiety-like behavior in mice.
The PhD presentation by Rony Paz suggested that aversive experiences can change how humans, particularly those with anxiety disorders, perceive stimuli. After a severe negative incident, patients with anxiety disorders over-generalize the experience and have increased emotional responses to subsequent similar situations.
The findings were presented at Neuroscience 2013.
--ANI (Posted on 12-11-2013)