health-news

New strategy to effectively treat and prevent osteoarthritis discovered

Washington, Mar. 26 : Researchers have found that adding lubricin - a protein that our bodies naturally produce - to the fluid in our joints may reduce the risk of or even prevent osteoarthritis (OA).


The discoveries were made in part by studying the knees of mice, which genetically lack lubricin, causing an aggressive arthritis in spite of high levels of hyaluronic acid in the synovial fluid.

A lack of lubricin, resulting in higher friction, leads to cartilage cell death - even in the presence of high levels of hyaluronic acid, a viscous fluid that cushions the joints.

This discovery appears to challenge the practice of injecting hyaluronic acid alone into a patient's joints.

"The lubricant is a protein, not hyaluronic acid, and currently, there are no disease-modifying treatments for osteoarthritis," Gregory D. Jay, M.D., Ph.D., of the department of emergency medicine, Rhode Island Hospital, said.

"Patients suffering from this degenerative joint disease either go through a total joint replacement, or are forced to live with pain every day.

"This discovery, however, supports that adding a lubricin replacement to the fluid in joints may in fact prevent osteoarthritis in those who have a genetic predisposition to the illness, or who have suffered significant trauma to the joints," he said.

Jay said that his team is working to create a replacement for natural lubricin that could significantly improve the treatment options and ultimately prevention measures.

The study has been published online in the journal Proceedings of the National Academy of Sciences.

--ANI (Posted on 26-03-2013)

health-news headlines

How food texture affects our calorie intake

Cheap 'magic' polypill helps fight heart diseases

Extroverts make for happier humans across cultures

Low-calorie restaurant menus may be making us unhealthier

Why rice is good for your health

Pregnant women with high BP risk preterm delivery and low birth weight

Casual marijuana use could lead to brain abnormalities in young adults

Antibiotics improve growth in kids in developing countries

Anti-depressants during pregnancy linked to autism and developmental delays in boys

Girls' mental health suffers when romances play out differently than they imagined

Now, faster, cheaper blood test to accurately diagnose asthma

Genetic therapy may repair spinal chord: Study

Quick Links: Goa | Munnar | Pondicherry | Free Yearly Horoscope '2014

Comments

Your e-mail:


Your Full Name:


Type verification image:
verification image, type it in the box

Message:

Back to Top