technology-news

New molecular breakthrough brings schizophrenia treatment closer to reality

Washington, Dec 31 : A researcher has discovered a basic cellular process that may contribute to the development of schizophrenia.


Now, Prof. Illana Gozes from the Sagol School of Neuroscience at Tel Aviv University has discovered that an important cell-maintenance process called autophagy is reduced in the brains of schizophrenic patients.

Autophagy is the process in which a membrane engulfs and consumes the clutter and it is essential to maintaining cellular health. But when autophagy is blocked, it can lead to cell death.

"We discovered a new pathway that plays a part in schizophrenia. By identifying and targeting the proteins known to be involved in the pathway, we may be able to diagnose and treat the disease in new and more effective ways," Prof. Gozes said.

Brain-cell death also occurs in schizophrenics, so Prof. Gozes and her colleagues set out to see if blocked autophagy could be involved in the progression of that condition as well.

They found RNA evidence of decreased levels of the protein beclin 1 in the hippocampus of schizophrenia patients, a brain region central to learning and memory.

Beclin 1 is central to initiating autophagy — its deficit suggests that the process is indeed blocked in schizophrenia patients. Developing drugs to boost beclin 1 levels and restart autophagy could offer a new way to treat schizophrenia, the researchers said.

The study is published in journal Nature's Molecular Psychiatry.

--ANI (Posted on 31-12-2013)

technology-news headlines

Internal body clock puzzle solved

Unearthed! Tilting planets can harbour life too

Infant hair reveals life inside the womb!

Now, 'second skin' that prevents dangerous sores in amputees

2014's first total lunar eclipse to create 'blood moon'

How black holes swallow stars

Asian air pollution affecting Northern Hemisphere's weather patterns

Now, bluetooth enabled footwear to help joggers from getting lost

Mars' atmosphere analyzing sensor could help cut Earth's greenhouse emissions

How flesh-eating bacteria exploded into epidemic

Birth of a baby moon on Saturn?

Robot sex to determine how life began!

Quick Links: Goa | Munnar | Pondicherry | Free Yearly Horoscope '2014

Comments

Your e-mail:


Your Full Name:


Type verification image:
verification image, type it in the box

Message:

Back to Top