Washington, Aug 3 IANS | 3 months ago

If you are suffering from chronic pain, it may affect the brain in such a way that it decreases your motivation level even after popping painkillers, says a study.

People with chronic pain report feeling fatigue, depression and decreased motivation, Neil Schwartz from Stanford University in California was quoted as saying.

The brain's rewiring during chronic pain may stem from the way pain prevents people from further injury, researchers said.

"Acute pain is useful because it limits or stops our behaviour to prevent further injury, promote healing and prevent a similar injury in the future," Schwartz added.

In their study, the researchers gave mice a chocolate-flavoured pellet if they poked their noses into a small hole.

But it became more difficult over time, requiring dozens of nose pokes for a pellet.

The injured mice still liked the reward but the pain decreased their motivation, the findings showed.

Even painkillers failed to improve their performance, researcher noted.

A signalling chemical called galanin was found to be the link between changes in the brain's circuits and the decreased level of motivation.

The researchers also found that some of the nerve cells in the nucleus accumbens, an area of the brain associated with pain and motivation, were not responding properly.

The study appeared in the journal Science.

(Posted on 03-08-2014)

Share This Page:

Post your comments

Information on States of India:

Andaman Nicobar | Andhra Pradesh | Arunachal Pradesh | Assam | Bihar | Chandigarh | Chhattisgarh | Dadar Nagar Haveli | Daman Diu | Delhi | Goa | Gujarat | Haryana | Himachal Pradesh | Jammu Kashmir | Jharkhand | Karnataka | Kerala | Lakshadweep | Madhya Pradesh | Maharashtra | Manipur | Meghalaya | Mizoram | Nagaland | Orissa | Pondicherry | Punjab | Rajasthan | Sikkim | Tamil Nadu | Tripura | Uttar Pradesh | Uttaranchal | West Bengal


Andhra Pradesh Travel Map | Bihar Travel Map | Goa Travel Map | Gujarat Travel Map | Haryana Travel Map | Himachal Pradesh Map | Karnataka Travel Map | Kerala Travel Map | Maharashtra Travel Map | Punjab Travel Map | Rajasthan Travel Map | Sikkim Travel Map | Tamil Nadu Travel Map | Uttar Pradesh Travel Map | West Bengal Travel Map |


Alappuzha | Ernakulam | Idukki | Kannur | Kasaragod | Kollam | Kottayam | Kozhikode | Malappuram | Palakkad | Pathanamthitta | Thiruvananthapuram | Thrissur | Wayanad |


Airports of India | Districts of India | India Pilgrim Centers | Tourism Map of India | National Highways in India | India Railway Routes |


Ahmadabad | Bangalore | Chennai | Coimbatore | Delhi | Hyderabad/Secunderabad | Kochi | Kolkata | Mumbai | Pondicherry | Pune | Surat |