New York, Aug 1 IANS | 3 months ago

There is good news for patients suffering from type-one diabetes as they may soon be able to do away with their daily insulin dose to manage their blood-sugar levels.


Researchers have found that a peptide called caerulein can convert existing cells in the pancreas into those cells destroyed in type-one diabetes-insulin-producing beta cells.

"We have found a promising technique for type-one diabetics to restore the body's ability to produce insulin," said Fred Levine, a professor at Sanford-Burnham Medical Research Institute in the US.

"By introducing caerulein to the pancreas, we were able to generate new beta cells - the cells that produce insulin," Levine added.

The study first examined how mice in which almost all beta cells were destroyed - similar to humans with type-one diabetes - responded to injections of caerulein.

In those mice, but not in normal mice, they found that caerulein caused existing alpha cells in the pancreas to differentiate into insulin-producing beta cells.

The research team then examined human pancreatic tissue from type-one diabetics, finding strong evidence that the same process induced by caerulein also occurred in the pancreases of those individuals.

Caerulein is a peptide originally discovered in the skin of Australian Blue Mountains tree frogs.

It stimulates gastric, biliary, and pancreatic secretions, and has been used in humans as a diagnostic tool in pancreatic diseases.

An estimated over 300 million people worldwide are living with type-one diabetes.

The study appeared in the journal Cell Death and Disease.

(Posted on 01-08-2014)

Share This Page:


Post your comments


Information on States of India:

Andaman Nicobar | Andhra Pradesh | Arunachal Pradesh | Assam | Bihar | Chandigarh | Chhattisgarh | Dadar Nagar Haveli | Daman Diu | Delhi | Goa | Gujarat | Haryana | Himachal Pradesh | Jammu Kashmir | Jharkhand | Karnataka | Kerala | Lakshadweep | Madhya Pradesh | Maharashtra | Manipur | Meghalaya | Mizoram | Nagaland | Orissa | Pondicherry | Punjab | Rajasthan | Sikkim | Tamil Nadu | Tripura | Uttar Pradesh | Uttaranchal | West Bengal

INDIA REGIONAL MAPS:

Andhra Pradesh Travel Map | Bihar Travel Map | Goa Travel Map | Gujarat Travel Map | Haryana Travel Map | Himachal Pradesh Map | Karnataka Travel Map | Kerala Travel Map | Maharashtra Travel Map | Punjab Travel Map | Rajasthan Travel Map | Sikkim Travel Map | Tamil Nadu Travel Map | Uttar Pradesh Travel Map | West Bengal Travel Map |

KERALA TRAVEL MAPS:

Alappuzha | Ernakulam | Idukki | Kannur | Kasaragod | Kollam | Kottayam | Kozhikode | Malappuram | Palakkad | Pathanamthitta | Thiruvananthapuram | Thrissur | Wayanad |

TRAVEL MAPS OF INDIA:

Airports of India | Districts of India | India Pilgrim Centers | Tourism Map of India | National Highways in India | India Railway Routes |

INDIA CITY MAPS:

Ahmadabad | Bangalore | Chennai | Coimbatore | Delhi | Hyderabad/Secunderabad | Kochi | Kolkata | Mumbai | Pondicherry | Pune | Surat |