Washington, Aug 1 IANS | 3 months ago

In a major breakthrough, scientists have transformed a mouse into a "see-through" creature that can give them a clearer view of the body tissues for research.

With the technique called CLARITY, the body of the mouse has been rendered transparent.

The method involves a water-based gel and detergents and can reveal all of an animal's organs - from its brain to its kidneys - while keeping them intact.

"This is the first study to perform whole-body clearing as opposed to first extracting and then clearing organs outside the adult body," said Viviana Gradinaru, a neuroscientist at California Institute of Technology in Pasadena.

The earlier method for rendering individual organs transparent had been used only in the case of brains and embryos.

Gradinaru and her team adapted the technique to use on whole mouse bodies.

The gel allowed them to remove the fatty molecules quickly.

In order to prevent tissue damage, they injected the gel and detergents directly into the rodent's bloodstream and within two to three days, organs like kidneys, heart, lungs and intestine turned transparent.

Within two weeks, the entire brain had turned clear as well, Live Science reported.

"We have also developed a solution for storing and imaging thick chunks of transparent tissue. Once tissue is stored in this way, scientists will be able to see the connections between cells, as well as the structures and molecules inside cells," researchers asserted.

The study was published in the journal Cell.

(Posted on 01-08-2014)

Share This Page:

Post your comments

Information on States of India:

Andaman Nicobar | Andhra Pradesh | Arunachal Pradesh | Assam | Bihar | Chandigarh | Chhattisgarh | Dadar Nagar Haveli | Daman Diu | Delhi | Goa | Gujarat | Haryana | Himachal Pradesh | Jammu Kashmir | Jharkhand | Karnataka | Kerala | Lakshadweep | Madhya Pradesh | Maharashtra | Manipur | Meghalaya | Mizoram | Nagaland | Orissa | Pondicherry | Punjab | Rajasthan | Sikkim | Tamil Nadu | Tripura | Uttar Pradesh | Uttaranchal | West Bengal


Andhra Pradesh Travel Map | Bihar Travel Map | Goa Travel Map | Gujarat Travel Map | Haryana Travel Map | Himachal Pradesh Map | Karnataka Travel Map | Kerala Travel Map | Maharashtra Travel Map | Punjab Travel Map | Rajasthan Travel Map | Sikkim Travel Map | Tamil Nadu Travel Map | Uttar Pradesh Travel Map | West Bengal Travel Map |


Alappuzha | Ernakulam | Idukki | Kannur | Kasaragod | Kollam | Kottayam | Kozhikode | Malappuram | Palakkad | Pathanamthitta | Thiruvananthapuram | Thrissur | Wayanad |


Airports of India | Districts of India | India Pilgrim Centers | Tourism Map of India | National Highways in India | India Railway Routes |


Ahmadabad | Bangalore | Chennai | Coimbatore | Delhi | Hyderabad/Secunderabad | Kochi | Kolkata | Mumbai | Pondicherry | Pune | Surat |