Washington, June 14 ANI | 2 months ago

A new study has revealed that anti-malarial drug hydroxychloroquine (HCQ) reverses resistance to tamoxifen, a widely used breast cancer drug, in mice.


According to the study by researchers from Georgetown Lombardi Comprehensive Cancer Center, adding HCQ to tamoxifen could provide a new treatment option for some women with advanced, postmenopausal estrogen receptor-positive (ER+) breast cancer.

The study found that the ER+ subtype accounts for an estimated 70 percent of all breast cancers.

The study's senior investigator, Robert Clarke, said that Tamoxifen resistance when treating breast cancer is a big issue in the clinic, and we believe our findings provide a very promising fix to the problem.

The study was published in Clinical Cancer Research.

(Posted on 14-06-2014)